Multifocal intraportal invasion of breast carcinoma diagnosed by laparoscopy-assisted liver biopsy

Figure 3 A: Laparoscopic liver biopsy from a wide scar lesion showed residual cancer cells scattered in a wide fibrous band in one area (hematoxylin and eosin (HE) stain). B and C: In another area intraportal tumor thrombi were clearly demonstrated. Endothelial cells were stained brown by CD31 immunohistochemistry (B, HE stain, C, CD31 immunohistochemical stain). D and E: Cancer cells showed desmoplastic change around them, which extended toward the sinusoids (D, HE stain, E, Masson’s trichrome stain). F: Original breast cancer. Note desmoplastic change around the tumor cells (HE stain).