Effects of fibril- or fixed-collagen on matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 production in the human hepatocyte cell line HLE

Figure 1 Effects of fibril type I collagen in the culture medium on the collagenase activity for type I collagen. Culture dishes were coated with or without type I collagen (10 μg/mL) and type IV collagen (10 μg/mL). For the control, cells were cultured without fibril collagen. ^bP<0.01 vs controls (Cont).