Nitroester drug’s effects and their antagonistic effects against morphine on human sphincter of Oddi motility

Table 4 Manometric data before and after administration of morphine in 30 patients (mean±SD).

	Before morphine administration (control)	10 min after morphine administration
Sphincter of Oddi basal pressure (mmHg)	7.37±5.58	16.60±13.87b
Amplitude of phasic contractions (mmHg)	54.09±38.37	100.70±43.51d
Frequency of phasic contractions (n/min)	7.15±3.20	10.38±2.93f
Common bile duct pressure (mmHg)	3.75±1.95	10.49±8.21h

^bP<0.01,

^dP<0.01,

^fP<0.01,

^hP<0.01 vs themselves, n = 30 (n represents the number of patients involved in the research).