Nitroester drug’s effects and their antagonistic effects against morphine on human sphincter of Oddi motility

Table 3 Manometric data before and after administration of PTN in 11 patients (mean±SD).

	Before PTN administration (control)	10 min after PTN administration	20 min after PTN administration
Sphincter of Oddi basal pressure (mmHg)	10.95±7.49	8.59±11.90	5.92±4.04a
Amplitude of phasic contractions (mmHg)	86.19±42.04	68.08±38.23	59.51±27.35
Frequency of phasic contractions (n/min)	7.04±1.50	5.95±2.79	7.31±2.80
Common bile duct pressure (mmHg)	7.26±4.25	4.83±4.13	5.57±3.49

^aP<0.05 vs themselves, n = 11 (n represents the number of patients involved in the research).