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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Apr 7, 2005; 11(13): 1929-1936
Published online Apr 7, 2005. doi: 10.3748/wjg.v11.i13.1929
Published online Apr 7, 2005. doi: 10.3748/wjg.v11.i13.1929
Figure 1 Molecular analysis of the coding TGF-β1 allele variations.
For analysis of the Leu10Pro (A), Arg25Pro (B) and Thr263Ile (C) TGF-β1 polymorphisms, corresponding sites are amplified using specific combinations of sense and reverse primers. Subsequently, fluorescently labeled hybridization probes are annealed to the amplicons allowing discrimination of the different alleles by melting curve analysis. Nucleotide positions are given according to GenBank accession nos. X05839 (Leu10Pro, Arg25Pro) and X05844 (Thr263Ile), respectively.
- Citation: Wang H, Mengsteab S, Tag CG, Gao CF, Hellerbrand C, Lammert F, Gressner AM, Weiskirchen R. Transforming growth factor-β1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection. World J Gastroenterol 2005; 11(13): 1929-1936
- URL: https://www.wjgnet.com/1007-9327/full/v11/i13/1929.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i13.1929