Inhibitory effect of tumor suppressor p33ING1b and its synergy with p53 gene in hepatocellular carcinoma

Table 1 G₀/G₁ cell cycle arrest analysis of hepatoma cells after cotransfection with p33^ING1b and wtp53 gene or control plasmids (mean±SD, %).

Cell line	Transfection plasmids	G0/G1 arrest
HepG2	p33ING1b	67.45±9.6a
	ap33ING1b	53.45±10.1
	p33ING1b+awtp53	55.61±8.3
	pcDNA3	58.78±10.3
PLC/PRF/5	p33ING1b	64.79±11.1
	p33ING1b+wtp53	78.16±10.5c
	ap33ING1b+ wtp53	60.17±9.8
	pcDNA3	56.56±8.8
Hep3B	p33ING1b	48.90±7.6
	p33ING1b+wtp53	55.91±10.1e
	ap33ING1b+ wtp53	50.92±8.5
	pcDNA3	52.87±7.0

^aP<0.05,

^cP<0.05, and

^eP>0.05 vs the control groups.