Study on hepatoprotective effect of peptide S-8300 from shark liver

Table 2 Effect of S-8300 on the GSH, SOD and MDA in mice injected with CCl₄.

Group	Dosage (mg/kg)	GSH (µg/mg prot)	SOD (U/mg prot)	MDA (nmol/mg prot)	General protein (mg/mL)
Normal control	–	27.75±0.86b	26.10±0.81b	0.55±0.025b	21.22±0.39
Model control	–	14.93±0.45	19.05±0.73	1.06±0.040	21.13±0.35
HGF	3	19.02±0.42b	21.82±0.82b	0.89±0.038b	21.28±0.49
S-8300	0.3	17.40±0.10b	21.19±0.69b	0.91±0.035b	21.3±0.29
	1	20.01±0.74b	23.39±0.42b	0.81±0.026b	21.11±0.44
	3	24.17±0.91b	24.51±1.01b	0.64±0.027b	21.3±0.43

^bP<0.01 vs model control.