Prognostic analysis of surgical treatment of peripheral cholangiocarcinoma: Two decades of experience at Chang Gung Memorial Hospital

Table 5 Univariate analysis of factors influencing the overall survival of the 312 PCC patients.

Factors	Survival time (mo)				P
	Median	mean	3-yr (%)	5-yr (%)
Mucobilia
Positive (n = 33)	24.07	45.79	40.3	25.65
Negative (n = 279)	6.48	13.05	7.41	3.89	<0.0001
Tumor spreading type
Papillary (n = 57)	22.59	38.19	31.77	20.42
Non-papillary (n = 255)	5.85	12.32	6.35	3.3	<0.0001
TNM staging
I (n = 17)	45.9	50.54	60.00	45
II (n = 58)	24.07	37.74	28.89	17.78
III (n = 88)	8.52	11.45	2.65	N.A
IV (n = 149)	4.18	7.66	6.08	N.A.	<0.0001
Tumor staging
Early stage (I+II) (75)	24.99	41.19	35.29	22.83
Advanced stage (III+IV) (237)	5.03	9.09	3.92	N.A.	<0.0001
Post-operative chemotherapy
With chemotherapy (n = 118)	11.44	24.25	17.74	11.88
Without chemotherapy (n = 194)	4.64	12.35	7.16	3.58	<0.0001
Post-operative radiotherapy
With radiotherapy (n = 63)	11.7	22.12	16.63	6.65
Without radiotherapy (n = 249)	6.25	15.89	9.65	7.17	0.0197