A Thai family with hereditary pancreatitis and increased cancer risk due to a mutation in PRSS1 gene

Figure 3 The schematic diagram of PRSS1 mutations discovered, to date, and their positions on the encoded protein. PRSS1 protein is shown with five regions, each of which encoded by a different exon, depicted with varying shaded blocks. The arrowheads represent the proteolysis cleavage sites of the protein resulting in various forms of trypsin biogenesis.