Metabolic changes in the lower esophageal sphincter influencing the result of anti-reflux surgical interventions in chronic gastroesophageal reflux disease

Table 3 Metabolic enzyme ratios in normal LES and in LES operated due to gastroesophageal reflux, as well as in patients with and without complaints in the postoperative period.

Enzymes	LES				P	LES in GERD				P
	Normal		GERD			Visick I		Visick II–III
	Mean	SE	Mean	SE	Mean	SE	Mean	SE
HBDH/LDH	0.337	0.009	0.319	0.006	P<0.001	0.321	0.009	0.318	0.008	NS
CK-MB/CK	0.005	0.003	0.006	0.003	NS	0.006	0.003	0.005	0.007	NS

LES: lower esophageal sphincter; GERD: gastroesophageal reflux disease; Visick I: symptom-free; Visick II–III: mild symptoms can be treated with medication; SE: standard error; P: significance; NS: non-significant; HBDH: α-hydroxybutyrate dehydrogenase; LDH: lactate dehydrogenase; CK-MB: creatine kinase MB; CK: creatine kinase.