Association of polymorphisms of interleukin-18 gene promoter region with chronic hepatitis B in Chinese Han population

Table 3 The association between genotypes of IL-18 promoter region polymorphisms and HBV copies in the chronic hepatitis B patients.

Polymorphism	Group I n = 97 (%)	Group II n = 134 (%)	χ2	P
Position -607
Genotypes
CC	23 (23.7)	39 (29.1)	0.83	0.361
CA	44 (45.4)	72 (53.7)	1.58	0.209
AA	30 (30.9)	23 (17.2)	6.03	0.014
Alleles
C	90 (46.4)	150 (56.0)	4.14	0.042
A	104 (53.6)	118 (44.0)
Position -137
Genotypes
GG	76 (78.4)	106(79.1)	0.021	0.89
GC	20 (20.6)	25 (18.7)
CC	1 (1.0)	3 (2.2)
Alleles
G	172 (88.7)	237 (88.4)	0.01	0.94
C	22 (11.3)	31 (11.6)

Group I: HBV-DNA <1×10³ copies/mL; Group II: HBV-DNA ≥1×10³ copies/mL. GG compared with both GC and CC.