Association of polymorphisms of interleukin-18 gene promoter region with chronic hepatitis B in Chinese Han population

Table 1 Comparison of IL-18 gene promoter polymorphism between patients with chronic hepatitis B and controls.

Polymorphism	Control n = 300 (%)	Patient n = 231 (%)	χ2	P
Position -607
Genotypes
CC	66 (22.0)	62 (26.8)	1.67	0.196
CA	160 (53.3)	116 (50.2)	0.51	0.476
AA	74 (24.7)	53 (23.0)	0.21	0.645
Alleles
C	292 (48.7)	240 (51.9)	1.12	0.842
A	308 (51.3)	222 (48.1)
Position -137
Genotypes
GG	202 (67.3)	182 (78.8)	8.55	0.003
GC	90 (30.0)	45 (19.5)	7.62	0.006
CC	8 (2.7)	4 (1.7)	0.52	0.472
Alleles
G	494 (82.3)	409 (88.5)	7.87	0.005
C	106 (17.7)	53 (11.5)