Effects of folic acid on epithelial apoptosis and expression of Bcl-2 and p53 in premalignant gastric lesions

doi:10.3748/wjg.v11.i11.1571

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Mar 21, 2005; 11(11): 1571-1576
Published online Mar 21, 2005. doi: 10.3748/wjg.v11.i11.1571

Table 2 Effects of folic acid on the apoptosis rate in gastric epithelial cells.

Group	n	Staining with PI (%)		Staining with annexin V FITC/PI (%)
Group	n	Pre-T	Post-T	Pre-T	Post-T
Treatment	19	6.19±2.82	6.78±2.15^b	16.22±3.80	21.00±4.61^a
Control	19	6.27±3.24	6.23±2.70	15.10±2.52	15.70±2.56

Apoptosis rate represents the ratio of Annexin V+/PI- cells to the total cell population. n: number; Treatment: treatment group; Control: control group; Pre-T: before treatment; Post-T: after treatment; Data are shown as (mean±SD)%.

^aP<0.05 and

^bP<0.01 vs control group and before treatment in the same group.

Citation: Cao DZ, Sun WH, Ou XL, Yu Q, Yu T, Zhang YZ, Wu ZY, Xue QP, Cheng YL. Effects of folic acid on epithelial apoptosis and expression of Bcl-2 and p53 in premalignant gastric lesions. World J Gastroenterol 2005; 11(11): 1571-1576
URL: https://www.wjgnet.com/1007-9327/full/v11/i11/1571.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i11.1571