Hepatocyte growth factor gene therapy prevents radiation-induced liver damage

Figure 2 Apoptotic activities (TUNEL analysis) in rat liver after 65 Gy of irradiation. A: EGT-control vector 2 d before liver irradiation; B: EGT-HGF 2 d before irradiation. Rats were sacrificed 2 d after irradiation and stained with TUNEL assay. Note the brown round stain indicated TUNEL-positive cells, which gathered around microvascular region. EGT-HGF almost completely protected rat liver from radiation-induced apoptosis; C: Percent of apoptotic cells were quantitated per 100 μm2 in areas shown on A and B. (P<0.05).