Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn’s disease: Phenotype-genotype correlations

Table 1 Clinical characteristics of the different cohorts of Crohn’s disease (CD) patients.

	Budapest (n = 185)	Veszprem (n = 175)	Szeged (n = 167)
Male/Female	98/87	88/87	79/88
Age (yr)	35.6±11.4	37.8±13.3	37.1±12.7
Age at presentation (yr)	27.2±10.3	30.2±12.4	28.9±10.9
Duration (yr)	8.9±6.6	7.7±6.8	8.0±7.3
Familial IBD, n (%)	63 (11.9)	38 (11.1)	25 (13.5)
Location (n) L1	43	54	39
L2	37	47	52
L3	103	74	74
L4	2	0	2
Behavior (n) B1	88	65	62
B2	40	39	49
B3	56	71	56
Perianal disease, n (%)	41 (22.1)	49 (28.0)	50 (29.9)
Frequent relapse, n (%)	59 (31.9)	72 (41.1)	64 (38.6)
Extraintestinal manifestations, n (%)	67 (36.2)	61 (34.8)	47 (28.2)
Operation, n (%)	77 (41.6)	76 (43.4)	67 (40.1)
Smoking habits (n) No	115	96	98
Yes	55	61	55
Previous	15	20	14