Vegetable/fruit, smoking, glutathione S-transferase polymorphisms and risk for colorectal cancer in Taiwan

Table 5 Combined effects of GST genotypes and vegetable/fruit consumption on colorectal cancer risk.

Genotype	Vegetable/fruit consumption	Men			Women
		Cases	Controls	OR (95%CI)1	Cases	Controls	OR (95%CI)2
GSTT1
Null	Low	106	69	1.00	90	62	1
Present	Low	101	74	0.87 (0.55-1.36)	54	66	0.60 (0.36-0.98)
Null	High	110	120	0.57 (0.37-0.88)	90	109	0.47 (0.30-0.75)
Present	High	91	145	0.32 (0.20-0.50)	81	88	0.53 (0.33-0.85)
P for interaction 0.21 0.06
GSTP1
With G	Low	60	49	1.00	44	35	1
A/A	Low	147	94	1.09 (0.67-1.76)	99	93	0.84 (0.49-1.45)
With G	High	71	73	0.73 (0.43-1.25)	46	64	0.51 (0.28-0.94)
A/A	High	130	193	0.40 (0.25-0.64)	125	133	0.58 (0.34-0.99)
P for interaction				0.03			0.42

¹Adjusted for age, physical activity, coffee, cigarette, alcohol, meat, vegetable/fruit and fish/shrimp;

²Adjusted for age, staple, meat, vegetable/fruit and fish/shrimp.