Vegetable/fruit, smoking, glutathione S-transferase polymorphisms and risk for colorectal cancer in Taiwan

Table 4 Combined genotype of GSTT1 and GSTP1 on colorectal cancer risk by tumor site and age in men.

	GSTT1 / GSTP1
	Present / (A/A)		Present /with G + null / (A/A)		Null /with G
	Cases/Controls	OR (95%CI)1	Cases/Controls	OR (95%CI)1	Cases/Controls	OR (95%CI)1
Total population2	132/157	1.00	205/191	1.42 (1.01-1.99)	71/60	1.91 (1.21-3.02)
Tumor site
Colon	64/157	1	88/191	1.16 (0.75-1.79)	31/60	1.42 (0.79-2.55)
Rectum2	68/157	1.00	117/191	1.65 (1.09-2.50)	40/60	2.20 (1.28-3.78)
Age at diagnosis
≤60 yr2	57/73	1.00	96/89	1.73 (1.04-2.89)	34/23	3.05 (1.51-6.12)
>60 yr	75/84	1.00	109/102	1.25 (0.78-2.02)	37/37	1.41 (0.75-2.64)

¹Adjusted for age, physical activity, coffee, cigarette, alcohol, meat, vegetable/fruit and fish/shrimp;

²Trend test P<0.01.