Vegetable/fruit, smoking, glutathione S-transferase polymorphisms and risk for colorectal cancer in Taiwan

Table 3 Odds ratio (OR) and 95% confidence interval (CI) of the polymorphisms of GSTM1, GSTT1 and GSTP1 for colorectal cancer by age at diagnosis and tumor site in women.

	GSTM1		GSTT1		GSTP1
	Present	Null	Present	Null	A/A	WithG2
Total population
Cases/Controls	126/130	189/195	135/154	180/171	224/226	90/99
OR (95%CI)1	1.0	0.99 (0.71-1.38)	1.0	1.18 (0.85-1.64)	1.0	1.00 (0.70-1.43)
Tumor site
Colon
Cases/Controls	61/130	105/195	72/154	94/171	116/226	49/99
OR (95%CI)1	1.0	1.19 (0.78-1.81)	1.0	1.23 (0.82-1.84)	1.0	1.04 (0.67-1.60)
Rectum
Cases/Controls	65/130	84/195	63/154	86/171	108/226	41/99
OR (95%CI)1	1.0	0.84 (0.56-1.27)	1.0	1.20 (0.79-1.81)	1.0	0.93 (0.60-1.46)
Age at diagnosis
≤60 yr
Cases/Controls	52/52	84/82	50/55	86/79	99/89	37/45
OR (95%CI)1	1.0	1.08 (0.63-1.85)	1.0	1.20 (0.71-2.05)	1	0.84 (0.48-1.47)
>60 yr
Cases/Controls	74/78	105/113	85/99	94/92	125/137	53/54
OR (95%CI)1	1.0	0.95 (0.61-1.46)	1.0	1.15 (0.75-1.76)	1.0	1.13 (0.71-1.80)

¹ORs and 95%CIs were estimated from multivariate unconditional logistic regressions controlling for age, sex, physical activity, coffee, cigarette, alcohol, meat, vegetable/fruit and fish/shrimp;

²Combined genotype of A/G and G/G.