Vegetable/fruit, smoking, glutathione S-transferase polymorphisms and risk for colorectal cancer in Taiwan

Table 2 Odds ratio (OR) and 95% confidence interval (CI) of the polymorphisms of GSTM1, GSTT1 and GSTP1 for colorectal cancer by age at diagnosis and tumor site in men.

	GSTP1		GSTP1		GSTP1
	Present	Null	Present	Null A/A	With	G2
Total population
Cases/Controls	195/193	213/215	192/219	216/189	277/287	131/122
OR (95%CI)1	1.0	0.93 (0.68-1.26)	1.0	1.45 (1.07-1.97)	1.0	1.36 (0.98-1.89)
Tumor site
Colon
Cases/Controls	82/193	101/215	89/219	94/189	127/287	56/122
OR (95%CI)1	1.0	1.00 (0.67-1.48)	1.0	1.24 (0.83-1.83)	1.0 1.15	(0.75-1.76)
Rectum
Cases/Controls	113/193	112/215	103/219	122/189	150/287	75/122
OR (95%CI)1	1.0	0.87 (0.61-1.25)	1.0	1.55 (1.08-2.23)	1.0	1.48 (1.00-2.18)
Age at diagnosis
≤60 yr
Cases/Controls	95/85	92/100	86/106	101/79	124/129	63/56
OR (95%CI)1	1.0	0.86 (0.53-1.30)	1.0	2.03 (1.29-3.21)	1.0	1.45 (0.89-2.37)
>60 yr
Cases/Controls	100/108	121/115	106/113	115/110	153/158	68/66
OR (95%CI)1	1.0	1.03 (0.67-1.58)	1.0	1.12 (0.73-1.71)	1.0	1.34 (0.84-2.12)

¹ORs and 95%CIs were estimated from multivariate unconditional logistic regressions controlling for age, physical activity, coffee, cigarette, alcohol, meat, vegetable/fruit and fish/shrimp;

²Combined genotype of A/G and G/G.