Expression patterns of transforming growth factor-beta and its receptors in gastric mucosa of patients with refractory gastric ulcer

Figure 5 In situ hybridization and immunohistochemistry localization of TGF-β and TGF-β receptor II in the gastric mucosa from patient 7. Serial sections were hybridized with antisense cRNA probes of TGF-β (A) and TGF-β receptor II (B), and stained with antibodies against TGF-β (C) and TGF-β receptor II (D). TGF-β mRNA was detected in the gastric epithelium and in the lamina propria (A). Expression of TGF-β mRNA was seen in the same region (B, arrowhead). Expression of TGF-β receptor II mRNA and TGF-β receptor II protein was also observed (C and D).