Expression patterns of transforming growth factor-beta and its receptors in gastric mucosa of patients with refractory gastric ulcer

Figure 4 In situ hybridization localization of TGF-β and TGF-β receptor II in the gastric mucosa from patients 5 (A, B and C) and 6 (D, E and F). Serial sections were hybridized as for patients 1 to 4. Slight TGF-β mRNA was seen in the gastric epithelium and lamina propria of patient 5 (A); very few signals could be detected in patient 6 (D). Expression of TGF-β receptor II mRNA was only minimally detected in the same region (B, arrowhead). No expression of TGF-β receptor II could be found in patient 6 (E).