Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: Comparison with Child-Pugh score and serum bile acid levels

Table 2 ¹³CO₂-peak and area under the curve (AUC) of ¹³CO₂ maximal scores in all groups of subjects studied.

Tests	CTR Mean (95% CI)	CH Mean (95% CI)	LCA Mean (95% CI)	LCB Mean (95% CI)	LCC Mean (95% CI)
13C- phenylalanine
13CO2-peak	12.68 (10.94-14.42)	16.11 (13.58-18.63)	11.85 (9.41-14.29)	10.45 (8.07- 12.83)	7.11 (2.74-11.47)
AUC13CO2max	5.40 (2.32-7.62)	6.85 (2.83-12.80)	5.81 (2.64-10.36)	4.60 (2.13-9.25)	5.40 (2.77-10.65)
13C-methacetin
13CO2-peak	31.03b (25.61-36.46)	22.80d (20.74-24.85)	19.19f (15.60-22.77)	10.18 (8.52-11.83)	7.02 (5.03-9.00)
AUC13CO2 max	16.76h (7.35-28.04)	14.69d (5.41-31.27)	9.44e (2.76-29.01)	4.91 (3.13-8.83)	5.32 (2.87-7.17)

CTR: Controls, CH: Chronic hepatitis, LCA: Child A cirrhosis, LCB: Child B, LCC: Child C ^bP<0.001 vs All groups ^dP<0.001 vs Child B,C. ^fP<0.01 vs Child B,C. ^hP<0.001 vs Child A,B,C. ^eP<0.05 vs Child B.