Amelioration of hemodynamics and oxygen metabolism by continuous venovenous hemofiltration in experimental porcine pancreatitis

Table 3 Oxygen metabolism parameters (mean±SD).

Parameter	Group	Baseline	6 h	12 h	24 h	36 h	48 h
DO2	1	774.1±142.9	1044.5±154.2d	1029.4±307.6	501.3±75.0d	389.4±178.8	NC
	2	751.4±206.0	811.6±197.4a	840.6±195.7	673.6±189.8	458.4±166.8c	320.9±71.8
	3	674.2±76.7	706.5±95.4a	552.1±119.7a	489.5±71.8bd	474.9±63.0d	517.2±163.7
VO2	1	215.3±44.9	336.6±103.1d	331.4±153.2	140.0±46.4d	108.0±55.1c	NC
	2	224.4±67.0	365.9±136.4d	331.0±70.0d	293.1±105.4a	200.6±133.8	93.7±41.9
	3	203.7±61.1	366.1±52.6d	247.8±73.7b	178.5±44.0b	163.2±45.1	167.8±90.0
OER	1	27.8±2.0	31.7±7.7	31.5±6.7	27.6±7.2	27.6±3.1	NC
	2	29.9±4.6	44.0±9.0ad	40.0±5.8ac	43.5±10.4ac	41.0±12.9	28.5±6.7
	3	30.0±6.8	51.9±3.2ad	44.6±7.3ad	36.3±7.2ad	33.9±6.4	31.0±7.8

DO₂: oxygen delivery, VO₂: oxygen consumption, OER: oxygen extraction ratio. Group 1: controls; group 2: low-volume continuous veno-venous hemofiltration (CVVH) (20 mL/kg body weight [BW]/h); group 3: high-volume CVVH (100 mL/kg BW); NC, not calculated (no survival).

^aP<0.05 and

^bP<0.01 vs the respective value in controls;

^cP<0.05 and

^dP<0.01 vs baseline values, respectively.