Amelioration of hemodynamics and oxygen metabolism by continuous venovenous hemofiltration in experimental porcine pancreatitis

Table 1 Clinical parameters (mean±SD).

Parameter	Group	Baseline	6 h	12 h	24 h	36 h	48 h
HR(bpm)	1	123.0±8.2	179±9.7d	194±20.8d	164±26.2c	132±23.0	NC
	2	123.0±8.2	159±10.4ad	165±15.5ad	159±21.6d	139±25.2	141±36.1
	3	125.0±8.3	149±9.9ad	155±23.8ad	148±21.4d	148±17.6d	138±18.4
BT(°C)	1	37.1±1.2	39.6±1.1d	40.0±0.9d	36.0±0.6c	35.6±0.6	NC
	2	37.9±0.7	38.7±1.2	38.7±0.6a	36.8±1.2c	36.1±1.3	37.5±3.4
	3	37.8±0.5	38.3±0.6ac	38.6±0.8a	38.8±0.8ac	38.5±0.2ac	39.0±0.3
Amy(U/l)	1	238.3±122.6	3635.0±427.2d	9535.8±5802.6d	7535.7±6573.6c	5502.7±1976.8c	NC
	2	336.0±123.8	3309.1±1331.2d	8199.4±5881.0d	8441.8±5730.6d	2960.5±1292.6c	3168.5±1136.3
	3	237.0±66.7	2803.9±518.1d	8186.6±3987.9d	8265.3±4092.0d	3211.9±1151.7d	2161.3±814.6

HR: heart rate, BT: body temperature, Amy: amylase. Group 1: controls; group 2: low-volume continuous veno-venous hemofiltration (CVVH) (20 mL/kg body weight [BW]/h); group 3: high-volume CVVH (100 mL/kg BW); NC, not calculated (no survival).

^aP<0.05 and ^bP<0.01 vs the respective value in controls;

^cP<0.05 and

^dP<0.01 vs baseline values, respectively.