1α, 25-dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital

Table 1 Body and liver masses in each group of rats at end of the study (after 20 wk) (mean ± SE)

Group	No. of rats	Body mass (g)	Liver mass (g)	Relative liver mass (g) (Liver/100 g body mass)
A	6	282.5 ± 15.8a	14.6 ± 2.6	5.16 ± 0.47b
B	10	338.0 ± 18.3	10.8 ± 1.9	3.19 ± 0.21
C	8	334.3 ± 13.8c	12.3 ± 1.8	3.67 ± 0.36e
D	10	348.9 ± 21.6	11.9 ± 1.5	3.41 ± 0.29
E	8	308.1 ± 19.1	13.1 ± 2.2	4.25 ± 0.45
F	10	336.6 ± 22.2	12.1 ± 1.8	3.59 ± 0.42

Statistical level of significance by using Dunnett’s t-test.

^aP < 0.05,

^bP < 0.01, significantly different from normal control (group B),

^cP < 0.05,

^eP < 0.05, significantly different from DEN control (group A).