Therapeutic polypeptides based on HBcAg18-27 CTL epitope can induce antigen-specific CD8+ CTL-mediated cytotoxicity in HLA-A2 transgenic mice

Figure 1 Detection of the HBcAg_18-27-specific CD8⁺ T cells produced with chimeric A2K^b/HBcAg_18-27 tetramer-binding assay. A: murine splenocytes from negative control mice, B: murine splenocytes from MART-1_27-35 irrelevant peptide immunized mice, C: murine splenocytes from peptide1 immunized mice, D: murine splenocytes from peptide2 immunized mice, E: murine splenocytes from peptide3 immunized mice.