C-reactive protein, procalcitonin, interleukin-6, vascular endothelial growth factor and oxidative metabolites in diagnosis of infection and staging in patients with gastric cancer

Table 2 Mean levels of VEGF, IL-6, PCT, CRP, MDA and NO in controls, cancer patients and in infection and non-infection groups of cancer patients

	Control (n = 23)	Gastric cancer (n = 42)	P value	Non-infection group (n = 23)	Infection group (n = 19)	P value
VEGF (pg/mL)	51.26 ± 30.04	489.28 ± 172.91b	< 0.000	462.84 ± 165.46	521.28 ± 180.72	NS
IL-6 (pg/mL)	1.41 ± 0.34	4.68 ± 2.00b	< 0.000	3.47 ± 0.77	6.15 ± 2.07d	< 0.000
PCT (ng/mL)	0.15 ± 0.065	0.59 ± 0.29b	< 0.000	0.42 ± 0.19	0.79 ± 0.27d	< 0.000
CRP (mg/L)	15.30 ± 11.28	78.21 ± 43.36b	< 0.000	57.83 ± 16.45	102.89 ± 52.71d	< 0.002
MDA(nmol/mL)	4.37 ± 2.99	11.42 ± 3.22b	< 0.000	9.85 ± 2.12	13.32 ± 3.35d	< 0.001
NO (µmol/L)	37.97 ± 6.35	49.32 ± 9.07b	< 0.000	45.79 ± 9.16	53.59 ± 7.06d	< 0.004

^bP < 0.000 vs control,

^dP < 0.005 vs non-infection group, NS: not significant.