Protein kinase C-dependent activation of P44/42 mitogen-activated protein kinase and heat shock protein 70 in signal transduction during hepatocyte ischemic preconditioning

Figure 6 Changes of cellular ultrastructure after treatment with IR, IP, IR+PMA, IP+CHE, and IP+PD98059. A: Effect of hypoxia reoxygenation on hepatocytes, B: Cytoprotective effects of hypoxic preconditioning, C: Preconditioning effects mimicked by stimulation of PKC with PMA, D: Preconditioning protection abolished by inhibition of PKC with chelerythrine, E: Cytoprotection of preconditioning reverted by PD98059.