Protective effects of rhubarb on experimental severe acute pancreatitis

Table 1 Effect of rhubarb on morphologic alterations in pancreas in rats with sever acute pancreatitis

Group	n	Edema	Hemorrhage	Vacuolization	Necrosis	PMN infiltration
Control	6	0	0	0	0	0
Rhubarb	6	0	0	0	0	0
Cerulein + Stress	9	2-3 (2.8 ± 0.2)	2-3 (2.8 ± 0.2)	2-3 (2.7 ± 0.2)	2-3 (2.5 ± 0.2)	2-3 (2.2 ± 0.2)
Cerulein + Stress + Rhubarb 75 mg	6	3 (3.0 ± 0)	1(1.0 ± 0)	2-3 (2.2 ± 0.2)	1-2 (1.4 ± 0.2)	1-2 (1.6 ± 0.2)
Cerulein + Stress + Rhubarb 150 mg	7	2-3 (2.8 ± 0.2)	1-2(1.0 ± 0.3)a	1-3 (1.8 ± 0.3)a	1-2 (1.2 ± 0.2)b	1-2 (1.8 ± 0.2)b

Values are expressed as the range of the scores, with the mean ± SD. The nonparametric test (Kruskal-Wallis method) showed

^aP < 0.05,

^bP < 0.01 vs Cn + St group; and no significant difference in edema.