Downregulation of retinoic acid receptor-&beta;2 expression is linked to aberrant methylation in esophageal squamous cell carcinoma cell lines

doi:10.3748/wjg.v10.i6.771

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Mar 15, 2004 (publication date) through Dec 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Esophageal Cancer

World J Gastroenterol. Mar 15, 2004; 10(6): 771-775
Published online Mar 15, 2004. doi: 10.3748/wjg.v10.i6.771

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Figure 3 Treatment with the indicated concentrations of 5-aza-dc induced demethylation and RARβ2 mRNA expression in ESCC cell lines. A: MSP analysis shows partial demethylation of the RARβ2 promoter region after 5-aza-dc treatment. B: RT-PCR analysis of RARβ2 mRNA expression before and af-ter 5-aza-dc treatment in cell lines that were found to have either positive (cell line KYSE180) or reduced (cell line KYSE410) baseline RARβ2 expression, GAPDH was used as internal control

Citation: Liu ZM, Ding F, Guo MZ, Zhang LY, Wu M, Liu ZH. Downregulation of retinoic acid receptor-β₂ expression is linked to aberrant methylation in esophageal squamous cell carcinoma cell lines. World J Gastroenterol 2004; 10(6): 771-775
URL: https://www.wjgnet.com/1007-9327/full/v10/i6/771.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i6.771