Association of FAS (TNFRSF6)-670 gene polymorphism with villous atrophy in coeliac disease

Table 2 Association of severity of villous atrophy with FAS-G670A polymorphism in untreated CD

Marsh	Genotype analysis			Allelic analysis
	GG genotype	GA genotype	AA genotype	OR1(95%CI)	G allele (%)	A allele (%)	OR2(95%CI)
	F/M	F/M	F/M
IIIa (%)	3/3 (15.0)	17/6 (57.5)	6/5 (27.5)	Reference	35 (44.0)	45 (56.0)	Reference
IIIb (%)	9/5 (21.5)	25/7 (49.2)	15/4 (29.2)	1.63 (0.56-4.76)	60 (46.0)	70 (54.0)	1.10 (0.63-1.93)
IIIc (%)	13/1 (34.1)3	18/2 (48.8)	7/0 (17.1)	3.74 (1.19-11.82)	48 (58.5)	34 (41.5)	1.81 (0.97-3.38)

F, women; M, men, OR¹, adjusted, for GG genotype frequency;

³P = 0.025, OR², adjusted, for G allele frequency.