Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver

Table 1 Effects of taurine on hepatic nuclear NTPase activity

Groups	NTPase activity (nmol/mg Pr per 10 min)
	ATP as substrate	GTP as substrate
Control	127 ± 7	150 ± 9
Taurine 10-6 mol/L	136 ± 9 (+7.1%)	168 ± 10 (+ 12.0%)a
Taurine 10-5 mol/L	148 ± 7 (+16.5%)b	179 ± 11 (+19.3%)b
Taurine 10-4 mol/L	150 ± 8 (+18.1%)b	191+12 (+27.3%)b

ATP and GTP were used as reaction substrates, respectively. The increases of the enzyme activities are indicated in paren-theses as percentage of the control. Mean ± SD, n = 6.

^aP < 0.05,

^bP < 0.01 compared with control.