Prognostic significance of preoperative circulating vascular endothelial growth factor messenger RNA expression in resectable hepatocellular carcinoma: A prospective study

doi:10.3748/wjg.v10.i5.643

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Mar 1, 2004 (publication date) through Jan 30, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Mar 1, 2004; 10(5): 643-648
Published online Mar 1, 2004. doi: 10.3748/wjg.v10.i5.643

Table 2 Predictors of HCC recurrence

Variable	P values
Variable	UV	MV
Sex	0.895	-
Age	0.279	-
Size(< 3 cm, > 10 cm)	0.415	-
Liver cirrhosis	0.510	-
Child-Pugh class	0.528	-
Serum AFP	0.744	-
HBsAg (+)	0.280	-
Anti-HCV (+)	0.481	-
Edmondson Steiner grade	0.0005	0.033
Capsule	< 0.0001	0.020
Vascular permeation	< 0.0001	0.018
Daughter nodules	< 0.0001	0.006
Tumor necrosis	0.344	-
Tumor hemorrhage	0.812	-
Serum VEGF₁₆₅ mRNA	0.0206	0.050
Serum VEGF₁₂₁ mRNA	0.520	-

UV: univariate analysis; MV: multivariate analysis; AFP: se-rum alpha fetoprotein; HbsAg(+): positive hepatitis B surface antigen; Anti-HCV(+): positive hepatitis C virus antibody; Edmondson Steiner grade: differentiation grade I, II vs III, IV; n.s: not significant.

Citation: Jeng KS, Sheen IS, Wang YC, Gu SL, Chu CM, Shih SC, Wang PC, Chang WH, Wang HY. Prognostic significance of preoperative circulating vascular endothelial growth factor messenger RNA expression in resectable hepatocellular carcinoma: A prospective study. World J Gastroenterol 2004; 10(5): 643-648
URL: https://www.wjgnet.com/1007-9327/full/v10/i5/643.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i5.643