Anti-neoplastic efficacy of Haimiding on gastric carcinoma and its mechanisms

Table 5 HMD at doses of 27.05 g/kg·d, 13.53 g/kg·d and 6.76 g/kg·d prolonged life span of H₂₂- bearing mice

Drug	Dose (g/kg)	Route	No.of animals	Life-span(d)	Rate of life prolongation (%)
HMD	27.05	iv	27	21.1 ± 1.6ac	74.4
HMD	13.53	iv	28	18.6 ± 2.9ac	53.7
HMD	6.76	iv	30	17.1 ± 3.2	41.3
HMD
Without 5-Fu	13.50	iv	30	15.8 ± 2.5	30.6
5-Fu	0.03	iv	29	14.6 ± 2.7	20.7
Normal saline		iv	30	12.1 ± 3.1

^aP < 0.05, ^bP < 0.01 vs HMD without 5-Fu;

^cP < 0.05, ^dP < 0.01 vs 5-Fu.