Esophageal Cancer
Copyright ©The Author(s) 2004.
World J Gastroenterol. Feb 15, 2004; 10(4): 476-480
Published online Feb 15, 2004. doi: 10.3748/wjg.v10.i4.476
Table 1 Expression of Egr-1, c-fos and cyclin D1 mRNAs and their proteins in esophageal precancerous lesions and cancer tissues
GroupsnEgr-1 positivity
c-fos positivity
cyclin D1 positivity
ISH(%)IHC (%)ISH(%)IHC(%)ISH(%)IHC(%)
Normal epithelia4213 (31.0)3 (7.1)2 (4.8)1 (2.4)2 (4.8)0 (0.0)
Simple hyperplasia5418 (33.3)8 (14.8)3 (5.6)3 (5.6)5 (9.3)3 (5.6)
Dysplasia4427 (61.4)21 (47.7)30 (68.2)29 (65.9)6 (13.6)6 (13.6)
Carcinoma in situ21 (50.0)1 (50.0)1 (50.0)1 (50.0)0 (0.0)0 (0.0)
Invasive carcinoma6812 (17.6)9 (13.2)35 (51.5)36 (52.9)35 (51.5)33 (48.5)