Modulation of tryptase secretion from human colon mast cells by histamine

Figure 4 Effect of histamine (hist) on anti-IgE or calcium iono-phore (CI) induced tryptase release from colon mast cells. The values shown are mean ± SEM for six separate experiments. Various concentrations of histamine were incubated with cells for 20 min before addition of anti-IgE or CI. ^aP < 0.05 compared with the corresponding histamine alone group (paired Student’s t test). Pred.hist + anti-IgE or CI = the sum of tryptase release induced by histamine alone and anti-IgE or CI alone.