Purification of heat shock protein 70-associated tumor peptides and its antitumor immunity on hepatoma in mice

Table 2 Comparison of tumor growth in mice immunized with HSP70-peptide complexes

Groups		Sex	No. of tumor-	10 days after HCaf challenge		15 days after HCaF challenge
				Size of tumor (mm3)	Inhibition rate (%)	Size of tumor (mm3)	Inhibition rate (%)
			bearing mice
HSP70	300 μg/kg	Female	2	0.88bc	97.0ac	6.66bd	98.5ad
		Male	6	61.98bd	80.2bd	384.77bc	83.2bc
	600 μg/kg	Female	1	0.45	98.4	5.74
		Male	6	64.49b	79.4bd	515.10bc	77.6bc
S-HCaF		Female	5	3.09bc	89.2bc	10.21bc	97.7bc
		Male	6	24.27bd	92.2bd	501.55b	78.2bd
S-HC		Female	6	30.00	-4.5	402.17	8.2
		Male	6	204.89	34.5	1554.30	32.3
PBS		Female	6	28.70		438.17
		Male	6	312.83		2295.52

^aP < 0.05, vs PBS;

^bP < 0.01, vs PBS;

^cP < 0.01, vs S-HC;

^dP < 0.05, vs S-HC. Inhibition rate (%)=1 - [(Tumor size of experimental group/Tumor size of control group(PBS)) × 100%]