Purification of heat shock protein 70-associated tumor peptides and its antitumor immunity on hepatoma in mice

Table 1 Comparison of survival time of tumor-bearing mice after immunized by HSP70-peptide complexes

Groups		Sex	No. of tumor-bearing/No. of mice challenged	Survival days of tumor-bearing (mean ± SD)	Extended survival rate (%)
			HSP70	300 μg/kg	Female	2/6	48.0 ± 8.5ad	67.4bd
Male	6/6	31.0 ± 13.2			49.7c
	600 μg/kg	Female	1/6	33
		Male	6/6	30.7 ± 12.7	48.4c
S-HCaF		Female	5/6	59.2 ± 10.0bd	106.5bd
		Male	6/6	20.3 ± 0.9	-2.0
S-HC		Female	6/6	24.0 ± 5.8	-16.3
		Male	6/6	18.5 ± 0.6	-10.5
PBS		Female	6/6	28.7 ± 11.6
		Male	6/6	20.7 ± 6.1

^aP < 0.05, vs PBS;

^bP < 0.01, vs PBS;

^cP < 0.01, vs S-HC;

^dP < 0.05, vs S-HC. Extended survival rate = [(MST of experimental group - MST of control group)/MST of control group] × 100%