Enhanced anti-apoptosis and gut epithelium protection function of acidic fibroblast growth factor after cancelling of its mitogenic activity

Figure 4 Morphological examination and immunohistochemical detection and quantification of apoptosis based on the label-ling of DNA strand breaks (Roche Applied Science, Germany). A: Marked epithelial separation from the basement, subepithelial edema, haemorrhage, erosion. C: Necrosis in I/R plus saline control group. E and G: Tissue damage reduction in both aFGF and aFGF28-154 treated groups. B: Immunohistochemical detection and quantification of apoptosis in normal epithelium entericum. D: Increased number of apoptotic cells in epithelium entericum in rats treated with saline. F and H: Significant reduction of apoptotic cells in epithelium entericum in rats treated with both aFGF and aFGF28-154.