Epstein-Barr virus in hepatocellular carcinogenesis

Figure 3 Results of immunohistochemistry. A: Positive-control of LMP1 from the tonsil tissue. The cytoplasm of lymphocytes showed positive signals. × 400, B: Immunohistochemical staining with anti-LMP1 antibody of an HCC specimen. The positive signals were localized in the cytoplasm and membrane of neoplasm cells. × 100, C: Immunohistochemical staining with anti-LMP1 antibody of an HCC specimen. The positive signals were localized in the cytoplasm and membrane of neoplasm cells. × 400, D: Immunohistochemical staining with anti-LMP1 antibody of an HCC specimen. The positive signals were localized in the nuclei of neoplasm cells. × 400, E: Immunohistochemical staining with anti-LMP1 antibody of an HCC specimen. The positive signals were localized in the interstitial lymphocytes but no clear positive signals were present in the adjacent neoplasm cells. × 400, F: Immunohistochemical staining with anti-HBsAg antibody of an HCC specimen. The positive signals were localized in the cytoplasm of neoplasm cells. × 400, G: Immunohistochemical staining with anti-HBcAg antibody of an HCC specimen. The positive signals were localized in the cytoplasm and nuclei of neoplasm cells. × 400, H: Immunohistochemical staining with anti-HCV antibody of an HCC specimen. The positive signals were localized in the nuclei of neoplasm cells. × 400.