Honokiol: A potent chemotherapy candidate for human colorectal carcinoma

doi:10.3748/wjg.v10.i23.3459

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Dec 1, 2004; 10(23): 3459-3463
Published online Dec 1, 2004. doi: 10.3748/wjg.v10.i23.3459

Table 1 Effect of honokiol on cell cycle distribution and apoptosis of RKO cells

Groups	Cell cycle distribution (%)			Apoptosis (%)
Groups	G0/G1	S	G2/M	Apoptosis (%)
ControL	44.45	45.10	10.14	0.27
5 μg/mL	48.03	42.37	9.60	4.51
10 μg/mL	54.04	40.30	5.66	14.10^a
15 μg/mL	58.94	39.36	1.70	20.31^b

^aP < 0.05,

^bP < 0.01 vs corresponding control group. Cell cycle distribution was determined after 48 h of treatment in each group. The tabulated percentages were an average calculated on the results of three separate experiments. The results were represented by mean ± SD (n = 3).

Citation: Chen F, Wang T, Wu YF, Gu Y, Xu XL, Zheng S, Hu X. Honokiol: A potent chemotherapy candidate for human colorectal carcinoma. World J Gastroenterol 2004; 10(23): 3459-3463
URL: https://www.wjgnet.com/1007-9327/full/v10/i23/3459.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i23.3459