Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis

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Dec 1, 2004 (publication date) through Jul 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Dec 1, 2004; 10(23): 3441-3454
Published online Dec 1, 2004. doi: 10.3748/wjg.v10.i23.3441

Table 5 Expression profile of the genes in the context of DNA methylation status

Methylation status	Positive rate % (Positive cases/the total cases)
Methylation status	CDH13	Cyclin a1	RAR-	COX2	P73	MGMT	hMLH1	p14ARF	TIMP3	CDH1
U	73 (16/22)	/	100 (8/8)	81 (35/43)	60 (12/20)	24 (11/46)	74 (35/47)	100 (51/51)	80 (46/58)	98 (57/58)
U/M	50 (14/28)	70 (37/53)	79 (22/28)	93 (14/15)	54 (19/35)	25 (2/8)	36 (4/11)	100 (2/2)	/	/
M	38 (3/8)	80 (4/5)	85 (17/20)	/	/	50 (2/4)	/	/	/	/
Total	57 (33/58)	71 (41/58)	84 (47/56)	84 (49/58)	53 (31/58)	26 (15/58)	67 (39/58)	100 (53/53)	79 (46/58)	98 (57/58)
Non-cancerous mucosa	+	/	++	/	+	+	++	+	+	++

Citation: Xu XL, Yu J, Zhang HY, Sun MH, Gu J, Du X, Shi DR, Wang P, Yang ZH, Zhu JD. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol 2004; 10(23): 3441-3454
URL: https://www.wjgnet.com/1007-9327/full/v10/i23/3441.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i23.3441