Liver Cancer
Copyright ©The Author(s) 2004.
World J Gastroenterol. Dec 1, 2004; 10(23): 3419-3423
Published online Dec 1, 2004. doi: 10.3748/wjg.v10.i23.3419
Table 2 Effect of PPARγ ligands on the incidence, multiplicity, and size of DEN-induced liver tumors in male Wistar rats (mean ± SD)
Experimental groupIncidence(%)1Histology
Tumor size(mm)1
HepatocarcinomaMultiplicity0-11-2> 2
DEN + basal diet13/30 (43)250.83 ± 1.222419
DEN + pioglitazone 200 ppm5/25 (20)a80.32 ± 0.75a323a