Coxsackievirus B3 infection and its mutation in Keshan disease

Figure 2 Positive signal of in situ hybridization in subacute myocardial tissue A: Feature positive signal of in situ hybridization with cardiac tissue is seen as deep brownish blue and seems to adhere onto myofibril, linked together in one or several strings of beads, when observed longitudinally (× 400); B: The granules of positive signal were thick and with clear border in varying size and localized in the sarcoplasm.