Copyright
©The Author(s) 2004.
World J Gastroenterol. Nov 15, 2004; 10(22): 3292-3298
Published online Nov 15, 2004. doi: 10.3748/wjg.v10.i22.3292
Published online Nov 15, 2004. doi: 10.3748/wjg.v10.i22.3292
Figure 5 Concentration-response curves for the contractile effect of (+)-cis-Dioxolane alone and in combination with different concentrations of M1 antagonist, pirenzepine (10-8 mol/L to 10-5 mol/L) on the rat antral circular smooth muscle strips.
Each point represents the mean ± SE, n = 6, 6, 7 and 8 strips. Cumulative concentration-effect curve was constructed for each strip for (+)-cis-Dioxolane, (10-8 to 3 × 10-5 mol/L). After washing, strips were equilibrated in either the absence (control) or presence of pirenzepine for 90 min. Subsequently, the second concentration-effect curve for (+)-cis-Dioxolane was constructed for each strip. Pirenzepine caused a significant inhibition of the contractile muscle response to (+)-cis-dioxolane.
- Citation: Wrzos HF, Tandon T, Ouyang A. Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats. World J Gastroenterol 2004; 10(22): 3292-3298
- URL: https://www.wjgnet.com/1007-9327/full/v10/i22/3292.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i22.3292