Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats

Figure 2 Effect of depletion of Ca²⁺ from medium on the contraction of antral circular smooth muscle strips to bethanechol (10^-4 mol/L). Ca²⁺ depletion caused a significant decrease in the muscle tension; after 5 min incubation (P < 0.06, paired t-test); and after 10 min incubation (P < 0.005, paired t-test) compared to the base contraction induced by bethanechol before Ca²⁺ depletion. Each data point represents mean ± SE, n = 3.