Effect of 2-(3-carboxy-1-oxopropyl) amino-2-deoxy-D-glucose on human esophageal cancer cell line

Table 1 Inhibitory effect of COPADG on the proliferation of esophageal cancer cell line Eca-109 (mean ± SD)

Concentration (mol/L)	A490nm			Inhibitory rate (%)
	24 h	48 h	72 h	24 h	48 h	72 h
0 (Control)	1.505 ± 0.090	1.686 ± 0.067	1.745 ± 0.077	12.76	20.81	31.29
0.01	1.313 ± 0.053b	1.336 ± 0.057b	1.199 ± 0.083b	12.76	20.81	31.29
0.03	0.958 ± 0.028	0.966 ± 0.086	0.900 ± 0.056	36.35	42.68	48.42
0.05	0.400 ± 0.064bc	0.429 ± 0.065ba	0.384 ± 0.050bc	73.42	74.57	77.99
0.07	0.383 ± 0.045	0.360 ± 0.039	0.342 ± 0.037	74.55	78.66	80.44
0.09	0.355 ± 0.046c	0.362 ± 0.053c	0.280 ± 0.039a	76.41	78.54	83.75

At the same time point, P < 0.01 vs the control group;

^bP < 0.01 vs 0.03 mol/L;

^aP < 0.05,

^cP > 0.05 vs 0.07 mol/L.