A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer

Table 1 Covariate distribution among study subjects and ORs for gastric cancer

	Characteristics	No Cases (%) (n = 165)	No. Controls (%) (n = 295)	OR (95%CI)
Age (yr)
	Mean (yr ± SD)	59.36 ± 9.29a	51.89 ± 10.24
	Min. (yr)	34.72	30.77
	Max. (yr)	81.95	78.21
Gender
	Male (%)	110 (66.67)	190 (64.41)
	Female (%)	55 (33.33)	105 (35.59)
	Ratio	2.00:1	1.81:1
Smoking habit
	Never	60 (36.36)	119 (40.34)	1.00
	Current	44 (26.67)	139 (47.12)	0.26 (0.15–0.46)b
	Past	61 (36.97)	37 (12.54)	3.15 (1.77–5.61)b
Alcohol habits
	Never	97 (58.79)	160 (54.24)	1.00
	Current	18 (10.91)	91 (30.85)	0.18 (0.10–0.35)b
	Past	50 (30.30)	44 (14.92)	1.80 (1.06–3.08)
Plasma H Pylori CagA antibody
	Negative	136 (82.42)	107 (49.31)	1.00
	Positive	29 (17.58)	110 (50.69)	0.18 (0.11–0.31)b
iNOS genotyping
	CC	108 (75.52)	189 (76.83)	1.00
	CT	33 (23.08)	49 (19.92)	1.15 (0.68–1.96)
	TT	2 (1.40)	8 (3.25)	0.42 (0.08–2.16)
	CT + TT	35 (24.48)	57 (23.17)	1.03 (0.59–1.79)

^aP < 0.05 vs control group after adjusted for age and gender,

^bP < 0.01 vs control.