Prognostic and clinicopathological features of E-cadherin, α-catenin, β-catenin, γ-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma

Table 2 The relationship between clinicopathology and the expression of cyclin D₁ E-cad and catenins

Type	Cases	CyclinD1		P	E-cad		P	α-cat		P	β-cat		P	γ-cat		P
		Positive	Negative		Preserved	Reduced		Preserved	Reduced		Preserved	Reduced		Preserved	Reduced
Histologicalgrade
I	16	6	10		5	11		7	9		10	6		8	8
II	35	15	20	> 0.05	5	30	< 0.05	11	24	> 0.05	24	11	> 0.05	19	16	< 0.05
III	11	6	5		0	11		1	10		6	5		3	8
Depth of invasion
T3	12	6	6	> 0.05	4	8	> 0.05	4	8	> 0.05	6	6	> 0.05	5	7	> 0.05
T4	50	31	19		6	44		15	35		34	16		25	25
Lymph node metastases
Positive	35	14	21	> 0.05	6	29	> 0.05	9	26	> 0.05	23	12	> 0.05	12	23	< 0.05
Negative	27	13	14		4	23		10	17		17	10		18	9