Maintaining cholesterol homeostasis: Sterol regulatory element-binding proteins

doi:10.3748/wjg.v10.i21.3081

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Nov 1, 2004 (publication date) through Nov 12, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 1, 2004; 10(21): 3081-3087
Published online Nov 1, 2004. doi: 10.3748/wjg.v10.i21.3081

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Figure 3 Metabolic pathways regulated by SREBPs G-6-P = glucose-6-phosphate; 6-PG = 6-phosphogluconate; Rib-5-P = ribulose-5-phosphate; PEP = phosphoenol pyruvate; CoA = coenzyme A; HMGCoA = 3-hydroxy-3-methylglutaryl coen-zyme A. SREBP-1c and SREBP-2 activate genes for the genera-tion of NADPH (ATP citrate lyase, malic enzyme, G-6-P dehydrogenase, 6-PG dehydrogenase) required in various steps of lipid synthesis.

Citation: Weber LW, Boll M, Stampfl A. Maintaining cholesterol homeostasis: Sterol regulatory element-binding proteins. World J Gastroenterol 2004; 10(21): 3081-3087
URL: https://www.wjgnet.com/1007-9327/full/v10/i21/3081.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i21.3081